Resort Review • Key West • Florida Keys

    Santa Maria Suites – Key West Resort Review

    Last updated: August 28, 2026

    Santa Maria Suites
    Santa Maria Suites – resort in Key West, Florida Keys
    AskTheKeys
    The AskTheKeys™ Verdict
    Who should choose Santa Maria Suites—and who shouldn't

    Choose Santa Maria Suites if...

    • You want a luxury two-bedroom suite with a full kitchen one block from Duval
    • You're a family or group needing space and room to cook and live comfortably
    • You want Old Town proximity without the noise of a Duval address

    Skip Santa Maria Suites if...

    • You want a simple traditional hotel room rather than a large suite
    • You want beachfront or marina access on-site
    • You're on a budget or want a mid-Duval nightlife address

    AskTheKeysAskTheKeys Traveler Match

    How well does Santa Maria Suites fit your trip?

    First-time visitors
    Couples / romance
    Beach-first travelers
    Families
    Walkable nightlife
    Travelers seeking value
    Excellent fit
    Good fit
    Consider alternatives

    Before you book — the one trade-off

    Santa Maria Suites is a block off the water with no beach of its own — you trade direct sand access for spacious luxury suites and full kitchens in quiet Old Town.

    AskTheKeysAskTheKeys Decision Summary

    Santa Maria Suites is best for travelers who want luxury two-bedroom suites with full kitchens and a quiet Old Town location one block from Duval. Not ideal for guests seeking a traditional hotel room, beachfront access, or a nightlife-forward base.

    Santa Maria Suites is a luxury all-suite resort on Simonton Street in Old Town Key West. Every unit is a two-bedroom suite with a full designer kitchen, washer/dryer, and separate living area. Two heated pools, complimentary happy hour, and daily turndown service. One block from Duval Street but noticeably quieter.

    Verified Live Rates

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    AskTheKeysBefore You Book

    The details that matter after you've narrowed down your options.

    Best for

    • Families needing space and full kitchen facilities
    • Extended-stay travelers who want to cook and live comfortably
    • Couples wanting luxury suites with privacy
    • Groups of up to 6 adults per suite
    • Guests who want Old Town proximity without Duval noise

    Not ideal for

    • Solo travelers or couples wanting a simple hotel room
    • Guests seeking beachfront or marina access
    • Budget travelers
    • Nightlife-first visitors wanting a mid-Duval address

    Quick facts

    Address1401 Simonton Street, Key West, FL 33040
    Phone+13052965678
    Check-in / Out4:00 PM / 11:00 AM
    ParkingPaid on-site
    PetsNo
    Beach accessNo
    Pool(s)Yes
    SpaNo
    EV chargingNo

    Location & nearby

    Santa Maria Suites is located in Old Town – South Duval / Simonton Corridor within Key West.

    What's nearby

    • Duval Street(0.1 mi, 1 min walk)
    • Southernmost Beach(0.2 mi, 4 min walk)
    • Key West Lighthouse & Keeper's Quarters(0.2 mi, 4 min walk)
    • Southernmost Point(0.3 mi, 5 min walk)
    • Key West Butterfly & Nature Conservatory(0.3 mi, 5 min walk)
    • Ernest Hemingway Home & Museum(0.3 mi, 6 min walk)
    • Mallory Square(0.7 mi, 14 min walk)
    • Fort Zachary Taylor State Park(0.7 mi, 14 min walk)

    Amenities overview

    Property highlight features

    • All two-bedroom suites with full designer kitchens
    • 2 heated outdoor pools with tropical gardens
    • Complimentary daily happy hour with wine and light fare
    • Daily turndown service with treats
    • On-site dining (Milagro Restaurant)

    Pricing positioning

    Typical nightly pricing tends to fall in the $$$$ range, depending on season and room type.

    luxury (seasonal)

    Verified Live Rates

    Compare current room availability and secure member-only pricing.

    We handle our lodging checks through Expedia's network engine so you can lock in hidden seasonal discounts and stack your One Key™ rewards points across different island brands.

    Check Rates & Availability on ExpediaOpens in a new window • No markup fees

    Independent Decision Engine

    Florida Keys Resorts operates as a fully objective, crowdsourced review system. We do not accept paid placements from hotels to alter their scoring records. Instead, we use standardized API connections to provide transparent third-party rate checks for our community.

    How Santa Maria Suites Compares to Other Key West Resorts

    Santa Maria Suites vs Casa Marina Key West

    • Santa Maria Suites wins:luxury all-suite with full kitchens and quiet Simonton Street location
    • Casa Marina Key West wins:historic beachfront resort with large pool, on-site beach, and full-service amenities

    Santa Maria Suites vs Southernmost Beach Resort

    • Santa Maria Suites wins:all-suite luxury with full kitchens one block from Duval
    • Southernmost Beach Resort wins:beachfront resort with tiki bar, multiple pools, and direct South Beach access

    Santa Maria Suites vs The Gardens Hotel

    • Santa Maria Suites wins:luxury two-bedroom suites with kitchens for families and groups
    • The Gardens Hotel wins:adults-only boutique inn set in a one-acre tropical garden for couples

    Santa Maria Suites vs The Southernmost House Key West

    • Santa Maria Suites wins:luxury all-suite resort with full kitchens for families and groups
    • The Southernmost House Key West wins:18-room adults-only historic mansion with oceanfront pool and breakfast

    FAQs

    Are all rooms at Santa Maria Suites two-bedroom?

    Yes. Every accommodation is a two-bedroom suite with approximately 960 square feet, a full designer kitchen, washer/dryer, and separate living area with queen sleeper sofa.

    Is Santa Maria Suites walkable to Duval Street?

    Yes. Santa Maria is on Simonton Street, one block from Duval. It is walkable to restaurants, bars, shops, and most Old Town attractions.

    Does Santa Maria Suites have a beach?

    No private beach, but Southernmost Beach is a 4-minute walk. The resort provides beach chairs and towels for guest use at nearby beaches.

    Is Santa Maria Suites good for families?

    Yes. The two-bedroom suites sleep up to 6, full kitchens reduce dining costs, and the washer/dryer handles family laundry. Two heated pools and a quiet setting suit families well.

    Does Santa Maria Suites include breakfast?

    No formal breakfast program, but the daily happy hour includes complimentary wine and light fare, and the full in-suite kitchen allows guests to prepare their own meals.

    What is the daily turndown service?

    Housekeeping provides an evening turndown with muffins, Dove ice cream bars, and chocolates — a signature Santa Maria touch.

    Is Santa Maria Suites adults-only?

    No. Families with children are welcome. The spacious suites and full kitchens make it one of the best family options in Old Town Key West.

    How does Santa Maria compare to a standard hotel room?

    Santa Maria suites are roughly 960 square feet with 2 bedrooms, 2 bathrooms, a full kitchen, and living area — approximately 3x the size of a typical Key West hotel room. The tradeoff is a higher nightly rate.